C5A ENHANCES DYSREGULATED INFLAMMATORY AND ANGIOGENIC RESPONSES TO MALARIA IN VITRO: POTENTIAL IMPLICATIONS FOR PLACENTAL MALARIA.

C5a enhances dysregulated inflammatory and angiogenic responses to malaria in vitro: potential implications for placental malaria.

Placental malaria (PM) is a leading cause of maternal and infant mortality.Although the accumulation of parasitized erythrocytes (PEs) and monocytes within Statue the placenta is thought to contribute to the pathophysiology of PM, the molecular mechanisms underlying PM remain unclear.Based on the hypothesis that excessive complement activation may

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